SAR131675

SAR131675

Cat. No.: DIA-0230297

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 1433953-83-3
Formula C18H22N4O4
Molecular Weight 358.39
SMILES CCN1C(=C(C(=O)NC)C(=O)C2=CC=C(N=C12)C#CC(C)(O)COC)N
Target VEGFR3
Product Description SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM in cell-free assays, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
Format & Storage
Purity > 99%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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