Sapanisertib (INK 128, MLN0128)

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Cat. No.: DIA-0230298

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1224844-38-5
Formula	C₁₅H₁₅N₇O
Molecular Weight	309.33
SMILES	CC(C)[N]1N=C(C2=CC3=C(OC(=N3)N)C=C2)C4=C(N)N=CN=C14
Target	mTOR
Product Description	Sapanisertib (INK 128, MLN0128) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin). Phase 1.

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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