Ruxolitinib (INCB018424)

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Cat. No.: DIA-0230311

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	941678-49-5
Formula	C₁₇H₁₈N₆
Molecular Weight	306.37
SMILES	N#CCC(C1CCCC1)[N]2C=C(C=N2)C3=NC=NC4=C3C=C[NH]4
Target	JAK1/2
Product Description	Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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