Cat. No.: DAB-0010997
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Host Species | Rat |
| Reactivity | Human |
| Applications | Flow Cyt |
| Product Description | Rat monoclonal antibody [bony-1] to Osteoprotegerin. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | TNFRSF11B |
| UniProt No. | O00300 |
| Gene ID | 4982 |
| Gene Description | Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Upon delivery aliquot and store at -20 °C. Avoid freeze / thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium azide; Constituent: PBS |
