Cat. No.: DAB-0012956
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Reactivity | Mouse |
| Applications | WB |
| Product Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly332 of mouse VMS1 protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | Ankzf1 |
| UniProt No. | Q80UU1 |
| Gene ID | 52231 |
| Gene Description | Mitochondria are membrane-bound subcellular organelles critical to many functions in eukaryotic cells. Several mechanisms have been found to play a role in mitochondria quality control. A recent study identified mitochondria-associated protein degradation as one such mechanism. The study showed that VMS1 interacts with VCP/Cdc48 and Npl4, two components in the endoplasmic reticulum-associated protein degradation pathway, and mediates the degradation of damaged mitochondrial proteins under stress conditions. Defective VMS1 compromises mitochondrial functions and cell viability. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
