Cat. No.: DAB-0012897
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IP |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human THEM2 protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | ACOT13 |
| UniProt No. | Q9NPJ3 |
| Gene ID | 55856 |
| Gene Description | THEM2 is a homotetrameric fatty acyl–CoA thioesterase. THEM2 and PC-TP, both enriched in liver, interact to form a complex. Cell membrane-bound phosphatidylcholines bind to PC-TP in the complex. The complex in turn inhibits IRS-2 and mTORC1, which leads to the suppression of insulin signaling. THEM2 has also been shown to regulate adaptive thermogenesis in mice. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
