Rabbit SPHK2 (D2V3G) Monoclonal Antibody

Rabbit SPHK2 (D2V3G) Monoclonal Antibody

Cat. No.: DAB-0012855

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human
Applications WB, IP
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly623 of human SPHK2 protein.
Format Liquid
Purity Affinity purity
Target Information
Target Name SPHK2
UniProt No. Q9NRA0
Gene ID 56848
Gene Description Sphingosine kinases catalyze the phosphorylation of sphingosine to form sphingosine-1-phosphate, a lipid mediator with both intra- and extracellular functions. Together with other sphingolipid metabolizing enzymes, SPHKs regulate the balance of the lipid mediators, ceramide, sphingosine, and S1P. Two distinct SPHK isoforms, SPHK1 and SPHK2, have been cloned and characterized. SPHK1 and SPHK2 are highly conserved and diversely expressed. The SPHKs are activated by G protein-coupled receptors, receptor tyrosine kinases, immunoglobulin receptors, cytokines, and other stimuli. The molecular mechanisms by which SPHK1 and SPHK2 are specifically regulated are complex and only partially understood.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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