Rabbit SOD2 (D3X8F) Monoclonal Antibody

Rabbit SOD2 (D3X8F) Monoclonal Antibody

Cat. No.: DAB-0012850

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human, Mouse, Rat, Monkey
Applications WB, IHC
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human SOD2 protein.
Format Liquid
Purity Affinity purity
Target Information
Target Name SOD2
UniProt No. P04179
Gene ID 6648
Gene Description Manganese superoxide dismutase is a mitochondrial detoxification enzyme that catalyzes the conversion of superoxide to hydrogen peroxide. Hydrogen peroxide is then decomposed to water by catalase, glutathione peroxidase, or peroxiredoxins. MnSOD/SOD2 and other enzymes involved in antioxidant defense protect cells from reactive oxygen species. Calorie restriction leads to SIRT3-mediated deacetylation of MnSOD/SOD2 and the subsequent increase of its antioxidant activity. MnSOD/SOD2 also plays an essential role in mediating the protective effect of mTOR inhibition to reduce epithelial stem cell senescence.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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