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Cat. No.: DAB-0012847
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IP |
| Product Description | Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human SNARK/NUAK2 protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | NUAK2 |
| UniProt No. | Q9H093 |
| Gene ID | 81788 |
| Gene Description | SNARK was identified as an SNF1/AMPK-related kinase and member of the AMPK catalytic subunit family. This enzyme was separately identified as a TNFα-induced SNF1-like kinase 2. The kinase activity of SNARK/NUAK2 is increased by AMP and AICAR. SNARK/NUAK2 activity is regulated by a variety of cellular stresses such as endoplasmic reticulum stress and oxidative stresses, suggesting that SNARK/NUAK2 is a signaling molecule involved in the cell stress response. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
