Rabbit SH3BP4 (D3D9I) Monoclonal Antibody

Rabbit SH3BP4 (D3D9I) Monoclonal Antibody

Cat. No.: DAB-0012830

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human, Monkey
Applications WB, IP
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val222 of human SH3BP4 protein.
Format Liquid
Purity Affinity purity
Target Information
Target Name SH3BP4
UniProt No. Q9P0V3
Gene ID 23677
Gene Description The mTORC1 kinase complex is a critical regulator of cell growth. Its activity is modulated by enviromental factors such as energy levels, growth factors, and amino acids. The GTPases RagA, RagB, RagC, and RagD mediate amino acid signaling to activate mTORC1. SH3BP4 binds to the inactive Rag GTPase complex during amino acid starvation and prevents the association of Rag GTPase complex with mTORC1 resulting in the suppression of mTORC1 activation and cell growth.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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