Cat. No.: DAB-0012819
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat, Hamster, Monkey |
| Applications | WB, IP, IHC, IF |
| Product Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly166 of human SDHA protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | SDHA |
| UniProt No. | P31040 |
| Gene ID | 6389 |
| Gene Description | Succinate dehydrogenase, also known as Complex II or succinate:quinone oxidoreductase, is a key component of the citric acid cycle and the electron transport chain. Specifically, it is involved in the oxidation of succinate. SDH consists of four subunits: SDHA, SDHB, SDHC, and SDHD. Research studies have shown that defects in SDHA cause complex II deficiency. In addition, investigators have observed reduction of SDHA in the striatum of patients with Huntington’s disease, and reduction of SDHB, SDHC, and SDHD in paragangliomas and phenochromocytomas. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
