Cat. No.: DAB-0012428
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala300 of human PGD protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | PGD |
| UniProt No. | P52209 |
| Gene ID | 5226 |
| Gene Description | 6-phosphogluconate dehydrogenase catalyzes the conversion of 6-phosphogluconate and NADP+ to ribulose 5-phosphate and NADPH in the pentose phosphate pathway. Research studies show that knockdown of PGD results in the induction of senescence and inhibition of growth of lung cancer cells. Additional research suggests that PGD influences the migration of some cancer cells by regulating c-Met phosphorylation state. Furthermore, it was shown that the glycolytic enzyme PGAM1 substrate regulates the pentose phosphate pathway by deactivating PGD/6PGD. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
