Cat. No.: DAB-0010469
Product Information | |
---|---|
Clonality | Monoclonal |
Isotype | IgG |
Host Species | Rabbit |
Reactivity | Human |
Applications | ICC, IF |
Product Description | Rabbit monoclonal antibody [EPR3358(2)] to PDX1. |
Format | Liquid |
Purity | Affinity purity |
Target Information | |
---|---|
Target Name | PDX1 |
UniProt No. | P52945 |
Gene ID | 3651 |
Gene Description | Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. |
Shipping & Storage | |
---|---|
Shipping | Shipped at 4 °C. |
Storage Instructions | Store at +4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle. Store In the Dark. |
Storage Buffer | pH: 7.40; Preservative: 0.02% Sodium azide; Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, PBS |