Cat. No.: DAB-0012305
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human |
| Applications | WB, IP |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MT-ATP8 protein. Antibodies are purified by peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | MT-ATP8 |
| UniProt No. | P03928 |
| Gene ID | 4509 |
| Gene Description | Mitochondrially-encoded ATP Synthase Membrane Subunit 8 is a product of MT-ATP8, one of 13 protein-encoding genes in the human mitochondrial genome. MT-ATP8 comprises one subunit of mitochondrial ATP synthase, the inner mitochondrial enzyme that catalyzes the final step of oxidative phosphorylation in the electron transport chain. Numerous mutations in MT-ATP8 have been identified that have deleterious effects on ATP synthase function, some of which manifest as debilitating neuronal and/or neuromuscular diseases, including epilepsy, schizophrenia, autism, ataxia, and various cardiomyopathies, underscoring the importance of healthy mitochondrial function to organismal health. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
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