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Cat. No.: DAB-0012303
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IP |
| Product Description | Polyclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MT-ATP6 protein. Antibodies are purified by peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | MT-ATP6 |
| UniProt No. | P00846 |
| Gene ID | 4508 |
| Gene Description | Mitochondrially-encoded ATP Synthase Membrane Subunit 6 is a product of MT-ATP6, one of 13 protein-encoding genes in the mitochondrial genome. MT-ATP6 comprises one subunit of the transmembrane F1FO ATP synthase, which catalyzes the final step of oxidative phosphorylation in the electron transport chain. A number of mutations in the MT-ATP6 gene have been identified that lead to defects in oxidative phosphorylation. Many of these are strongly associated with distinct disease states, including Leigh syndrome and Charcot-Marie-Tooth disease. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
