Cat. No.: DAB-0011650
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Applications | Target binding affinity, Antibody labelling |
| Product Description | HRP Rabbit monoclonal antibody [EP318Y] to Hamartin. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | TSC1 |
| UniProt No. | Q92574 |
| Gene ID | 7248 |
| Gene Description | In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at +4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle. Store In the Dark. |
| Storage Buffer | pH: 7.40; Preservative: 0.1% Proclin 300; Constituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS |
