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Cat. No.: DAB-0012136
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat, Hamster, Monkey |
| Applications | WB |
| Product Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala131 of human HMOX2/HO-2 protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | HMOX2 |
| UniProt No. | P30519 |
| Gene ID | 3163 |
| Gene Description | Heme oxygenases catalyze the rate-limiting step of the oxidative degradation of heme into iron, carbon monoxide, and biliverdin. Biliverdin is then converted to bilirubin. Heme is a strong pro-oxidant whereas bilirubin is a strong antioxidant. Research studies suggest disregulation of heme oxygenases may contribute to oxidative stress-related diseases. There are three isozymes of heme oxygenases: HMOX1/HO-1, HMOX2/HO-2, and HMOX3/HO-3. HMOX1/HO-1 is inducible by heme and other stress stimuli. HMOX2/HO-2 and HMOX3/HO-3 are constitutively expressed. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
