Rabbit FAAH1 ( Specific) Polyclonal Antibody

Rabbit FAAH1 ( Specific) Polyclonal Antibody

Cat. No.: DAB-0012005

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Polyclonal
Host Species Rabbit
Reactivity Rat
Applications WB, IP
Product Description Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of rat FAAH1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Format Liquid
Purity Affinity purity
Target Information
Target Name FAAH
UniProt No. O00519
Gene ID 2166
Gene Description Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse. Fatty-acid amide hydrolase 1 is a plasma membrane-bound hydrolase that converts oleamide to oleic acid. This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation. Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo. FAAH1 null mice also demonstrate an increased preference for alcohol and an increased voluntary uptake of alcohol as compared to wild-type mice, indicating a role of FAAH1 in modulating addictive behaviors.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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