Rabbit eNOS (phospho Ser1177) (C9C3) Monoclonal Antibody

Rabbit eNOS (phospho Ser1177) (C9C3) Monoclonal Antibody

Cat. No.: DAB-0012484

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human, Bovine, Pig
Applications WB, IP
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser1177 of human eNOS.
Format Liquid
Purity Affinity purity
Target Information
Target Name NOS3
UniProt No. P29474
Gene ID 4846
Gene Description Endothelial nitric-oxide synthase is an important enzyme in the cardiovascular system. It catalyzes the production of nitric oxide, a key regulator of blood pressure, vascular remodeling, and angiogenesis. The activity of eNOS is regulated by phosphorylation at multiple sites. The two most thoroughly studied sites are the activation site Ser1177 and the inhibitory site Thr495. Several protein kinases including Akt/PKB, PKA, and AMPK activate eNOS by phosphorylating Ser1177 in response to various stimuli. In contrast, bradykinin and H2O2 activate eNOS activity by promoting both Ser1177 phosphorylation and Thr495 dephosphorylation.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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