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Cat. No.: DAB-0011956
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IF, Flow Cyt |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human DDX6/RCK protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | DDX6 |
| UniProt No. | P26196 |
| Gene ID | 1656 |
| Gene Description | DDX6, also known as RCK and p54, was identified as a proto-oncogene product and is a member of the ATP-dependent DEAD box helicase family. This protein interacts with translation initiation factor eIF4E in the cytoplasmic P-bodies and represses mRNA translation. DDX6 is a component of the miRNA induced silencing complex and interacts with Argonaute 1 and Argonaute 2 proteins in vitro and in vivo, functioning in miRNA-mediated translational repression. Depletion of DDX6 leads to the disruption of cytoplasmic P-bodies indicating that it is required for P-body formation. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
