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Cat. No.: DAB-0011897
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG |
| Host Species | Rabbit |
| Reactivity | Human |
| Applications | WB, IP |
| Product Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Phe727 of human Ceruloplasmin protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | CP |
| UniProt No. | P00450 |
| Gene ID | 1356 |
| Gene Description | Ceruloplasmin is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe2+ to Fe3+, facilitating iron transport across the cell membrane. Mutation in Ceruloplasmin causes aceruloplasminemia, an autosomal recessive disorder of iron metabolism characterized by iron accumulation in the brain as well as visceral organs, resulting in retinal degeneration, diabetes mellitus and neurological disturbances. Ceruloplasmin level in serum has been explored as a diagnostic marker for Wilson disease and ischemic heart disease. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
