Rabbit C/EBPβ (LAP) Polyclonal Antibody

Rabbit C/EBPβ (LAP) Polyclonal Antibody

Cat. No.: DAB-0011857

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Polyclonal
Host Species Rabbit
Reactivity Human, Mouse
Applications WB
Product Description Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal sequence of human C/EBPbeta. Antibodies are purified by protein A and peptide affinity chromatography.
Format Liquid
Purity Affinity purity
Target Information
Target Name CEBPB
UniProt No. P17676
Gene ID 1051
Gene Description CCAAT/enhancer-binding proteins are a family of transcription factors critical for cellular differentiation, terminal functions, and inflammatory response. Six members of the family have been characterized and are distributed in a variety of tissues. There are two forms of C/EBPβ, the 38 kDa liver activating protein and the 20 kDa liver inhibitory protein which may be products of alternative translation. The 38 kDa LAP protein is a transcriptional activator while LIP may act as an inhibitor of C/EBPβ transcriptional activity. Phosphorylation of C/EBPβ at distinct sites stimulates its transcriptional activity. Phosphorylation at serine 105 of rat C/EBPβ, a unique site only present in the rat sequence, seems essential for rat C/EBPβ activation.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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