Cat. No.: DAB-0011888
Product Information | |
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Clonality | Monoclonal |
Isotype | IgG |
Host Species | Rabbit |
Reactivity | Human |
Applications | WB, IP, IF |
Product Description | Monoclonal antibody is produced by immunizing animals with recombinant human CD10/Neprilysin protein. |
Format | Liquid |
Purity | Affinity purity |
Target Information | |
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Target Name | MME |
UniProt No. | P08473 |
Gene ID | 4311 |
Gene Description | CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen, or neutral endopeptidase, is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts promote tumor formation and chemoresistance. |
Shipping & Storage | |
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Shipping | Shipped at 4 °C. |
Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
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