Rabbit Branched-Chain Amino Acid Metabolism Sampler Kit Monoclonal Antibody

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Cat. No.: DAB-0011851

Size: 20 µL Size: 100 µL Size: Customer Size

Product Information
Clonality	Monoclonal
Host Species	Rabbit
Product Description	Monoclonal antibodies are produced by immunizing animals with synthetic peptides corresponding to residues near the amino terminus of human BCAT1 protein, residues surrounding Leu39 of human BCAT2 protein, residues near the carboxy terminus of human BCKDH-E1α protein, and a synthetic phosphopeptide corresponding to residues surrounding Ser292 of mature human BCKDH-E1α protein, which corresponds to Ser293 of mature mouse BCKDH-E1α protein and Ser293 of mature rat BCKDH-E1α protein.
Format	Liquid
Purity	Affinity purity

Target Information
Gene Description	BCAT1 and BCAT2 are cytosolic and mitochondrial branched chain aminotransferases, respectively. Research studies have implicated BCAT1 in distant metastasis in patients with advanced colorectal cancer. Disruption of BCAT2 in mice leads to higher levels of plasma branched-chain amino acids, reduced adiposity and body weight, and increased energy expenditure, suggesting its role in regulating insulin sensitivity.

Target Information

Gene Description

BCAT1 and BCAT2 are cytosolic and mitochondrial branched chain aminotransferases, respectively. Research studies have implicated BCAT1 in distant metastasis in patients with advanced colorectal cancer. Disruption of BCAT2 in mice leads to higher levels of plasma branched-chain amino acids, reduced adiposity and body weight, and increased energy expenditure, suggesting its role in regulating insulin sensitivity.

Shipping & Storage
Shipping	Shipped at 4 °C.
Storage Instructions	Store at +4 °C short term (1-2 weeks). Store at -20 °C long term.
Storage Buffer	Constituent: 100% PBS

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.