Rabbit Aurora A/AIK (1G4) Monoclonal Antibody

Rabbit Aurora A/AIK (1G4) Monoclonal Antibody

Cat. No.: DAB-0011828

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human, Monkey
Applications WB, IF
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human Aurora A/AIK.
Format Liquid
Purity Affinity purity
Target Information
Target Name AURKA
UniProt No. O14965
Gene ID 6790
Gene Description Aurora A is a cell cycle-regulated Ser/Thr protein kinase that is overexpressed in many tumor cell lines. Phosphorylation of Aurora A at Thr288 within the kinase activation loop results in a significant increase in its activity and may target the protein for proteasomal degradation during mitosis. The closely-related kinase Aurora B has been implicated in multiple mitotic events, and siRNA silencing of Aurora B expression results in reduced histone H3 phosphorylation, aberrant chromosome alignment/segregation, and altered survivin localization.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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