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Cat. No.: DAB-0011732
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val348 of human ALDH2 protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | ALDH2 |
| UniProt No. | P05091 |
| Gene ID | 217 |
| Gene Description | Aldehyde dehydrogenase 2 is a member of the aldehyde dehydrogenase superfamily. The enzymes in this family catalyze the oxidation of a variety of aldehydes, leading to their detoxification. ALDH2 activation correlates with decreased ischemic heart injury, suggesting an essential role of ALDH2 in cardiac protection from ischemic injury. In addition, ALDH2 is the primary enzyme for aldehyde oxidation in hematopoietic stem cells. ALDH2 is required for protecting these cells from DNA damage caused by acetaldehyde and has a critical function to counteract genotoxicity. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
