Cat. No.: DAB-0011730
Product Information | |
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Clonality | Monoclonal |
Isotype | IgG |
Host Species | Rabbit |
Reactivity | Human |
Applications | WB, IF, Flow Cyt |
Product Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro9 of human ALDH1A2 protein. |
Format | Liquid |
Purity | Affinity purity |
Target Information | |
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Target Name | ALDH1A2 |
UniProt No. | O94788 |
Gene ID | 8854 |
Gene Description | The aldehyde dehydrogenase family is a large group of enzymes that catalyze the oxidization of aldehydes into carboxylic acids. Aldehyde Dehydrogenase 1A2 is among a group of aldehyde dehydrogenases that catalyze the metabolism of retinaldehyde into retinoic acid, which plays a critically important signaling role in animal development. Research studies have shown that ALDH1A2 also plays a role postnatally in modulating the effects of RA signaling on immune cell function. In one example using a genetic mouse model, it was shown that ALDH1A2-dependent RA signaling was a downstream mediator of NOTCH-dependent T cell differentiation. |
Shipping & Storage | |
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Shipping | Shipped at 4 °C. |
Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
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