Cat. No.: DAB-0011694
| Product Information | |
|---|---|
| Clonality | Polyclonal |
| Host Species | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Product Description | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val74 of human ADH1B protein. Antibodies are purified by protein A and peptide affinity chromatography. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | ADH1B |
| UniProt No. | P00325 |
| Gene ID | 125 |
| Gene Description | Human alcohol dehydrogenase genes are grouped into five classes, with three distinct class I ADH genes and ADH4, ADH5, ADH7 and ADH6 belonging to classes II, III, IV, and V, respectively. ADH is a zinc-containing, dimeric enzyme that catalyzes the conversion of cytosolic alcohol to acetaldehyde in the liver with the coenzyme NAD. ADH1A is monomorphic and is the predominant fetal and neonatal liver ADH enzyme. In contrast, polymorphic ADH1B and ADH1C enzymes are predominant in adult livers. Polymorphisms in the human class I ADH genes result in functionally variable ADH enzymes; evidence suggests that specific variants may provide protection from the risk of alcoholism. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
