Rabbit Acetyl-CoA Carboxylase (C83B10) Monoclonal Antibody

Rabbit Acetyl-CoA Carboxylase (C83B10) Monoclonal Antibody

Cat. No.: DAB-0011683

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Reactivity Human, Mouse, Rat, Hamster
Applications WB, IHC, IF, Flow Cyt
Product Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser523 of human acetyl-CoA carboxylase α1.
Format Liquid
Purity Affinity purity
Target Information
Target Name ACACA
UniProt No. Q13085
Gene ID 31
Gene Description Acetyl-CoA carboxylase catalyzes the carboxylation of acetyl-CoA to malonyl-CoA. It is the key enzyme in the biosynthesis and oxidation of fatty acids. In rodents, the 265 kDa ACC1 form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 is the main isoform in oxidative tissues. However, in humans, ACC2 is the predominant isoform in both lipogenic and oxidative tissues. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at -20 °C. This product will freeze at -20 °C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Storage Buffer Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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