Rabbit Acetyl-CoA Carboxylase 1 Polyclonal Antibody

Rabbit Acetyl-CoA Carboxylase 1 Polyclonal Antibody

Cat. No.: DAB-0011684

Size: 20 µL Size: 100 µL Size: Customer Size
Product Information
Clonality Polyclonal
Host Species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IP
Product Description Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human acetyl-CoA carboxylase 1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Format Liquid
Purity Affinity purity
Target Information
Target Name ACACA
UniProt No. Q13085
Gene ID 31
Gene Description Acetyl-CoA carboxylase catalyzes the carboxylation of acetyl-CoA to malonyl-CoA. It is the key enzyme in the biosynthesis and oxidation of fatty acids. In rodents, the 265 kDa ACC1 form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 is the main isoform in oxidative tissues. However, in humans, ACC2 is the predominant isoform in both lipogenic and oxidative tissues. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at –20 °C. Do not aliquot the antibody.
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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