R406 (free base)

R406 (free base)

Cat. No.: DIA-0230353

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 841290-80-0
Formula C22H23FN6O5
Molecular Weight 470.45
SMILES COC1=C(OC)C(=CC(=C1)NC2=NC(=C(F)C=N2)NC3=NC4=C(OC(C)(C)C(=O)N4)C=C3)OC
Product Description R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3.
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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