Porcine Osteoprotegerin ELISA Kit (OPG)

Porcine Osteoprotegerin ELISA Kit (OPG)

Cat. No.: DAA-001322

Size: 1 x 96 tests Size: 10 x 96 tests Size: Customer Size
Product Information
Product Name Porcine Osteoprotegerin ELISA Kit (OPG)
Species Pig
Description Porcine Osteoprotegerin ELISA Kit (OPG) is an in-vitro enzyme-linked immunosorbent assay for the quantitative measurement of porcine Osteoprotegerin in serum, plasma and cell culture supernatants. This assay employs an antibody specific for porcine Osteoprotegerin coated on a 96-well plate. Standards and samples are pipetted into the wells and Osteoprotegerin present in a sample is bound to the wells by the immobilized antibody. The wells are washed, and biotinylated anti-porcine Osteoprotegerin antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of Osteoprotegerin bound.
Sample Types Cell Culture Supernatant, Serum, Plasma
Detection Range 0.123 ng/mL - 30 ng/mL
Sensitivity 0.12 ng/mL
Target Information
Target Name TNFRSF11B
UniProt No. O00300
Gene ID 4982
Target Description Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Alternative Names MGC29565; OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNF receptor superfamily member 11b; TNFRSF 11B; TNFRSF11B; TR 1; TR1; TR11B_HUMAN; Tumor necrosis factor receptor superfamily member 11B
Shipping & Storage
Sipping Shipping on dry ice.
Storage Store at -20°C. Please refer to protocols.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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