PLX-4720

Inquiry

Cat. No.: DIA-0230397

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	918505-84-7
Formula	C₁₇H₁₄ClF₂N₃O₃S
Molecular Weight	413.83
SMILES	CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(Cl)C=C23
Target	c-Raf-1
Product Description	PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.