Cat. No.: DIA-0230404
Product Information | |
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CAS No. | 20069-09-4 |
Synonyms | PPLGM, Piplartine |
Formula | C17H19NO5 |
Molecular Weight | 317.34 |
SMILES | COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O |
Target | PI3K/Akt/mTOR |
Product Description | Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1 also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells. |
Format & Storage | |
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Purity | > 98% |
Shipping | Shipped on dry ice. |
Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
Solubility Overview | Soluble in DMSO |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.