Picropodophyllin (PPP)

Picropodophyllin (PPP)

Cat. No.: DIA-0230418

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 477-47-4
Synonyms AXL1717
Formula C22H22O8
Molecular Weight 414.41
SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(O)C4=CC5=C(OCO5)C=C24
Target IGF-1R/IR
Product Description Picropodophyllin (PPP) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R).
Format & Storage
Purity > 99%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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