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Cat. No.: DIA-0243105
| Product Information | |
|---|---|
| CAS No. | 114-86-3 |
| Synonyms | Phenethylbiguanide |
| Formula | C10H15N5 |
| Molecular Weight | 205.26 |
| SMILES | NC(NC(NCCC1=CC=CC=C1)=N)=N |
| Target | Mitochondrial Metabolism, AMPK, Apoptosis |
| Product Description | Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis. |
| Format & Storage | |
|---|---|
| Shipping | Room temperature in the continental U.S. Other areas may vary. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
