Cat. No.: DIA-0243223
Product Information | |
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CAS No. | 1011528-58-7 |
Formula | C21H28O5 |
Molecular Weight | 360.44 |
SMILES | O[C@H]1[C@@]23[C@](CC[C@]4([H])[C@]3([H])CC5=C(C=CO5)[C@@H]4C)([H])[C@@](CO1)(CCC2)C(OC)=O |
Target | Salt-inducible Kinase (SIK) |
Product Description | Phanginin A is a potent and orally active SIK1 (salt-induced kinase 1) activator. Phanginin A inhibited gluconeogenesis. Phanginin A increases the expression of p-SIK1 and decreases the expression of p-CREB. Phanginin A reduces blood glucose levels and improves glucose tolerance and dyslipidemia. Phanginin A has the potential for the research of type 2 diabetes. |
Format & Storage | |
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Shipping | Room temperature in the continental U.S. Other areas may vary. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.