PF-06409577

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Cat. No.: DIA-0230441

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1467057-23-3
Formula	C₁₉H₁₆ClNO₃
Molecular Weight	341.79
SMILES	OC(=O)C1=C[NH]C2=CC(=C(C=C12)C3=CC=C(C=C3)C4(O)CCC4)Cl
Product Description	PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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