Pamapimod (R-1503, Ro4402257)

Inquiry

Cat. No.: DIA-0230459

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	449811-01-2
Formula	C₁₉H₂₀F₂N₄O₄
Molecular Weight	406.38
SMILES	CN1C(=O)C(=CC2=CN=C(NC(CCO)CCO)N=C12)OC3=C(F)C=C(F)C=C3
Product Description	Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.

Format & Storage
Purity	> 98%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.