Cat. No.: DMM-001007
| Status | Age | Sex |
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| Product Overview | |
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| Model Description | NONcNZO10/LtJ is a recombinant congenic strain to model human obesity-induced Type 2 diabetes and Metabolic Syndrome. Type 2 diabetes in males of this strain results from polygenic interactions producing a moderate obesity rather than the massive obesity elicited by mutations in the leptin/leptin receptor axis. Unlike mice with monogenic obesity syndromes, NONcNZO10/LtJ males do not exhibit hypercorticism, are not hyperphagic, and show no obvious thermoregulatory defects. |
| Strain Name | NONcNZO10/LtJ |
| Background Strain | NON/Lt |
| SPF | Yes |
| Research Application | Diabetes |
