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* Services or Products of Interest (DIA-0243110) Nerigliatin
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* All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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Nerigliatin

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Cat. No.: DIA-0243110

Size: 100 mg Size: 200 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1245603-92-2
Synonyms	PF-04937319
Formula	C₂₂H₂₀N₆O₄
Molecular Weight	432.43
SMILES	O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C
Target	Glucokinase
Product Description	Nerigliatin (PF-04937319) is a glucokinase activator (GKA) with EC50 value of 154.4 ?μM, one of the most promising strategies for the treatment of type 2 diabetes mellitus. Nerigliatin is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs.

Format & Storage
Format	Solid
Color	White to yellow
Purity	99.78%
Shipping	Room temperature in the continental U.S. Other areas may vary.
Storage	Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 6 months; -20°C, 1 month
Solubility Overview	Soluble in DMSO

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.