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Cat. No.: DAB-0012879
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Host Species | Mouse |
| Reactivity | Human |
| Applications | IHC |
| Product Description | Monoclonal antibody is produced by immunizing animals with a myeloma cell line. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | SDC1 |
| UniProt No. | P18827 |
| Gene ID | 6382 |
| Gene Description | Syndecans are a family of type 1 transmembrane heparan sulphate proteoglycans comprising four members in mammals encoded by four syndecan genes. Syndecans are involved in embryonic development, tumorigenesis, and angiogenesis. The extracellular domain harbors attachment sites for heparan sulfate and chondroitin sulfate chains, facilitating interaction with an array of proteins including a plethora of growth factors. In addition, the hydrophobic C-terminal intracellular domain can interact with proteins containing a PDZ domain. These interactions place syndecans as important integrators of membrane signaling. Syndecans undergo proteolytic cleavage causing the release of their extracellular domain, converting the membrane-bound proteins into soluble molecular effectors. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Stored at 4 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in a Tris-based buffer with 1% BSA and less than 0.1% sodium azide. Stable for 24 months when |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
