Mouse S6 Ribosomal Protein (54D2) Monoclonal Antibody

Mouse S6 Ribosomal Protein (54D2) Monoclonal Antibody

Cat. No.: DAB-0012810

Size: 20 µg Size: 100 µg Size: Customer Size
Product Information
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Reactivity Human, Mouse, Rat, Monkey, D. melanogaster
Applications WB, IHC, IF, Flow Cyt
Product Description Monoclonal antibody is produced by immunizing animals with a recombinant fusion protein corresponding to full-length human S6 ribosomal protein. The epitope corresponds to a region surrounding Asp20 of human S6 ribosomal protein.
Format Liquid
Purity Affinity purity
Target Information
Target Name RPS6
UniProt No. P62753
Gene ID 6194
Gene Description One way that growth factors and mitogens effectively promote sustained cell growth and proliferation is by upregulating mRNA translation. Growth factors and mitogens induce the activation of p70 S6 kinase and the subsequent phosphorylation of S6 ribosomal protein. Phosphorylation of S6 ribosomal protein correlates with an increase in translation of mRNA transcripts that contain an oligopyrimidine tract in their 5' untranslated regions. These particular mRNA transcripts encode proteins involved in cell cycle progression, as well as ribosomal proteins and elongation factors necessary for translation. Important S6 ribosomal protein phosphorylation sites include several residues located within a small, carboxy-terminal region of S6 protein.
Shipping & Storage
Shipping Shipped at 4 °C.
Storage Instructions Store at -20 °C. This product will freeze at -20 °C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Storage Buffer Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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