Mouse Models

Mouse Models

Mouse models allow for relevant study of diabetes and can mimic human diabetes, aiding in investigating disease mechanisms, identifying biomarkers, and testing potential treatments. There are three main forms of diabetes based on the underlying causes: type 1, type 2, and gestational diabetes. Mouse models bridge the gap between basic research and clinical translation, making them essential for advancing diabetes treatment and prevention.

Fig. 1 T2DM

The T1DM mouse models are genetically modified mice that develop a similar autoimmune response, resulting in hyperglycemia and insulin deficiency. The T1DM mouse models are powerful tools for studying disease mechanisms, identifying biomarkers, and testing potential therapies.

Fig. 2 T2DM

Mouse models for T2DM study are generated by feeding mice a high-fat or high-sugar diet or genetically modifying mice to develop obesity and insulin resistance. T2DM mouse models are important for studying disease mechanisms, identifying potential therapeutic targets, and testing new treatments.

Fig. 3 GDM

GDM mouse models involve feeding mice a high-fat or high-sugar diet during pregnancy or genetically modifying mice to develop impaired glucose tolerance and insulin resistance during pregnancy. GDM mouse models are very important for studying disease mechanisms, identifying biomarkers, and testing potential therapies for gestational diabetes.

Ace Therapeutics offers mouse models for diabetes study classified by types of diabetes with guaranteed quality and efficiency. If you couldn't find what you need, please feel free to contact us and get started with our customized service.

Mouse Models for Diabetes Research
C57BL/6J-Hjvem1 Mouse (DMM-001141)
  • Target Name: Hjv
  • Backgrounds: C57BL/6J
  • Target Name: Mcoln1
  • Backgrounds: C57BL/6J
  • Target Name: Col3a1
  • Backgrounds: C57BL/6J
C57BL/6J-Vcanem1 Mouse (DMM-001144)
  • Target Name: Vcan
  • Backgrounds: C57BL/6J
  • Target Name: Serpinf1
  • Backgrounds: C57BL/6J
  • Target Name: Fem1b
  • Backgrounds: C57BL/6J
  • Target Name: Mir29a, Mir29b1
  • Backgrounds: C57BL/6J
  • Target Name: Col5a1
  • Backgrounds: C57BL/6J
  • Target Name: Prkci
  • Backgrounds: C57BL/6J
  • Target Name: Psma1
  • Backgrounds: C57BL/6J
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Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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