Cat. No.: DAB-0010019
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Host Species | Mouse |
| Reactivity | Human, Rat, Sheep, Horse, Bovine, Dog, Non-human primates |
| Applications | WB, ICC, IF, Flow Cyt |
| Product Description | Mouse monoclonal antibody [5-2H10] to FTO. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | FTO |
| UniProt No. | Q9C0B1 |
| Gene ID | 79068 |
| Gene Description | Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at -20 °C. Stable for 12 months at -20 °C. |
| Storage Buffer | Constituents: 0.238% HEPES, 0.01% BSA, 50% Glycerol, 0.87% Sodium chloride |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
