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Cat. No.: DAB-0011761
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Host Species | Mouse |
| Reactivity | Human |
| Applications | WB, IP |
| Product Description | Monoclonal antibody is produced by immunizing animals with a purified recombinant fragment of human ApoM protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | APOM |
| UniProt No. | O95445 |
| Gene ID | 55937 |
| Gene Description | Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. Chylomicrons are a fundamental class of apolipoproteins containing very low-density lipoproteins, intermediate-density lipoproteins, low-density lipoproteins, and high-density lipoproteins .Apolipoprotein M is a novel membrane bound apolipoprotein involved in lipid transport. ApoM primarily interacts with HDL and regulates its metabolism. It is highly expressed in hepatocytes and kidney proximal tubule cells. Recently, ApoM was shown to act as a vasculoprotective constituent of HDL by delivering S1P to the S1P receptor on endothelial cells. SNPs of ApoM have been associated with type 2 diabetes. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
