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Cat. No.: DAB-0011736
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Host Species | Mouse |
| Reactivity | Human |
| Applications | WB |
| Product Description | Monoclonal antibody is produced by immunizing animals with a recombinant protein fragment specific to human ALPP protein. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | ALPP |
| UniProt No. | P05187 |
| Gene ID | 250 |
| Gene Description | Mammalian alkaline phosphatases are highly conserved zinc-containing allosteric enzymes that are able to hydrolyze and transphosphorylate a wide range of compounds. There are four known human alkaline phosphatase isozymes: TNAP, ALPP, ALPP2, and ALPI. Placental alkaline phosphatase is bound to the plasma membrane via a glycosyl-phosphatidylinositol anchor. It is expressed primarily in the placenta and may be involved in transplacental IgG transport. ALPP has been found to be overexpressed on the surface of several different types of solid tumor cells and elevated serum concentrations of ALPP and ALPP-like enzymes has been found to be associated with ovarian, cervical, and testicular cancer. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | Store at –20 °C. Do not aliquot the antibody. |
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
