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Cat. No.: DAB-0013065
| Product Information | |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Host Species | Mouse |
| Reactivity | Human |
| Product Description | Recombinant human adiponectin purified from E.coli. |
| Format | Liquid |
| Purity | Affinity purity |
| Target Information | |
|---|---|
| Target Name | ADIPOQ |
| UniProt No. | Q15848 |
| Gene ID | 9370 |
| Gene Description | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped at 4 °C. |
| Storage Instructions | This product is shipped at ambient temperature. It is recommended to aliquot and store at -20 °C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8 °C for short term use (up to 4 weeks) and store the remaining aliquots at -20 °C. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| Storage Buffer | Phosphate buffered saline <0.1% Sodium Azide (NaN3) |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
