Mazdutide

Inquiry

Cat. No.: DIA-0243174

Size: 10 mg Size: 25 mg Size: 50 mg Size: 100 mg Size: Customer Size

Product Information
CAS No.	2259884-03-0
Synonyms	IBI-362; LY-3305677; OXM-3
Formula	C₂₁₀H₃₂₂N₄₆O₆₇
Molecular Weight	4563.06
Target	GCGR, GLP Receptor
Product Description	Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and?glucagon receptor?(GCGR). Mazdutide binds human and mouse?GCGR?(Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates?insulin?secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D).

Format & Storage
Format	Solid
Color	White to off-white
Purity	99.74%
Shipping	Room temperature in the continental U.S. Other areas may vary.
Storage	In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solubility Overview	Soluble in water

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.