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Cat. No.: DIA-0230603
| Product Information | |
|---|---|
| CAS No. | 2088939-99-3 |
| Formula | C33H45Cl4N3O2 |
| Molecular Weight | 657.54 |
| SMILES | Cl.Cl.CC(C)CN(CC(C)C)CC(=O)N1CCN(CC1)CC(OCC2=CC=C3C=CC=CC3=C2)C4=CC=C(Cl)C=C4Cl |
| Target | ULK1 |
| Product Description | LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants. |
| Format & Storage | |
|---|---|
| Purity | > 99% |
| Shipping | Shipped on dry ice. |
| Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
| Solubility Overview | Soluble in DMSO |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
